The water level was high enough to prevent the animal from touching the base of the tank and low enough to prevent animal from jumping out of the water
On the one hand, ROS in higher concentration, are likely to influence STAT3 signaling indirectly by inhibiting protein tyrosine phosphatases and activating protein kinases, which in turn increases STAT3 phosphorylation (44, 45)
J Am Coll Cardiol 35(7):17781784 Diguet N, Trammell SAJ, Tannous C, Deloux R, Piquereau J, Mougenot N, Gouge A, Gressette M, Manoury B, Blanc J, Breton M, Decaux JF, Lavery GG, Baczk I, Zoll J, Garnier A, Li Z, Brenner C, Mericskay M (2018) Nicotinamide riboside preserves cardiac function in a mouse model of dilated cardiomyopathy
[1] Drge W, Breitkreutz R
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